Diabetes is the most common condition these days which affects millions of people on the earth. There are no age bars because it affects all age group. So, the treatment of diabetes is not yet confirmed but there are several ways which can help to control blood sugar. Now, the researchers at the University of North Carolina at Chapel Hill and North Carolina State University at Raleigh have discovered another option to control diabetes. They created a synthetic patch which can be filled with natural beta cells that can secrete doses of insulin to control blood sugar levels on demand without the risk of inducing hypoglycemia. This creation of insulin patch is the proof of concept builds on an innovative technology and the “smart insulin patch” was reported last year in the Proceedings of the National Academy of Sciences. These two patches are thin polymeric squares about the size of a quarter and covered in tiny needles, like a miniature bed of nails.
Whereas, the former insulin patch was filled with human made bubbles of insulin and this new integrates the needles with live beta cells. Former was known as smart insulin patch and this new one is known as “smart cell patch”. The test of this painless patch is done on the small animals which can be the model of type 1 diabetes and result shows that it could quickly respond to skyrocketing blood sugar levels and significantly lower them for 10 hours at a time. Result of this painless patch were published in the journal Advanced Materials. Zhen Gu, PhD, assistant professor in the joint University of North Carolina and North Carolina State department of biomedical engineering said that this study provides a potential solution for the tough problem of rejection, which has long plagued studies on pancreatic cell transplants for diabetes. Additionally, it demonstrates that we are able to build a bridge between the physiological signals within the body and these therapeutic cells outside the body to keep blood sugar levels under control.
Beta cells works as the body’s natural insulin manufacturer and it resides in the pancreases. In a healthy human being, it works to produce store, and release the hormone insulin in order to process the sugar that builds up in the blood stream after having a mean. In diabetic people, these beta cells get either damaged or they are not able to produce enough insulin which can keep the blood sugar under control. As we know that diabetes is affecting million of people in the world and who are suffering from type 1 diabetes and advanced type 2 diabetes, always monitor their blood sugar level and try to keep it under control. In order to keep blood glucose level under control, diabetic people inject themselves with variety of insulin which are very painful and imprecise. If they inject wrong amount of medicines, it can lead to significant complications such as blindness and limb amputations or even more disastrous consequences such as diabetic comas and death.
Researchers have researcher transplantation of insulin-producing cells as an alternative treatment for diabetes and first successful transplant of human beta cells was performed in 1990. After that hundreds of diabetic patients have undergone the procedure. Now most transplants are rejected, and many of the medications used to suppress the immune system wind up interfering with the activity of beta cells and insulin. This new painless patch are applied to the skin, the patch’s micro needles poked into the capillaries and blood vessels that forms a connection between the internal environment and the external cells of the patch. So, now you can control your blood sugar level by just applying this painless patch.
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