Infertility in men and women has become the epidemic and all scientists, researchers and health experts are doing their all efforts to treat these diseases with most success rate. Just last week, United Kingdom Human Fertilization and Embryology Authority (HFEA), who are the regulators of United Kingdom for fertility matters granted the permission to the scientists in London, United Kingdom to make the changes in their genes in order to treat infertility. This is like an endorsement of such research which is done by national regulatory authority. According to this endorsement, people can be aware of that Human Fertilization and Embryology Authority (HFEA) has approved the application to use the technique of gene-editing like CRISPR-Cas9. In this process a healthy embryos should alter the genes that are active in the first few days after getting fertilized by a development biologist. In this process, the researchers will stop doing experiment after seven day because after which researched embryo will be spoiled. This research will help the researchers to find the better development of treatment for infertility by doing modification of genes, although the embryos will not comprise the basis of treatment themselves.
In this world here are so many countries that have no such national regulatory authority may proceed to use the technique of gene-editing CRISPR-Cas9 for as the infertility treatment. Researchers may use the healthy human embryos which have been left over in fertility clinics after In Vito Fertilization (IVF) procedure. Scientists from London receives the approval plan so that they can block the activity of a master regulators gene which is active in cells and go onto the form the human fetus. Researchers says that after this research they will be able to discover how a healthy human develops by examining the very earliest stages of human development, thereby improving their understanding of in vitro fertilization success rates. However, while approving the research application to use the technique of gene-editing CRISPR-Cas9, the Human Fertilization and Embryology Authority (HFEA) stipulated that a local research ethics committee in the UK will need to evaluate and approve the research proposed by the researchers before such research could begin.
This report has brought a reverberating effect in all over the world and particularly in those countries where they were considering regulating this technology. Well this is a well-regulated system around world that is able to clearly make the differences between research in this area and reproduction. In the United Kingdom using gene-editing CRISPR-Cas9 technique to conceive a child is considered as illegal but many other countries have not yet considered legislation that addresses this new and emerging field. Now the decision to allow embryo-editing research could further perform the reason of debate over whether the gene-editing technique should be used for infertility treatment purposes only, or also in germ-line editing (editing genes that will be passed on to children).
Some countries do not explicitly prohibit using gene-editing CRISPR-Cas9 technique to get pregnant. Consequently, the research that got the approval letter just last week may further serve to teach us the potential risks which is involved in this gene-editing procedure for infertility treatment to be passed on to children to prevent certain hereditary diseases.
What is gene therapy?
Gene therapy is a different kind of procedure from gene editing procedure. In gene editing procure, health experts cuts out the bad or undesired gene from the DNA and replaces it with a healthy gene and gene therapy uses the procedure where they doesn’t involve any splicing out the ‘bad’ gene, but they make the addition of new genes to the patient’s cells in the hope that they will be taken up and replace missing or malfunctioning genes. For this process, researchers use the virus to carry the genetic material in to cells because virus customarily enters in to the cells to live and survive under the cells of body. So if a gene has mutated and it causes a protein that is vital to our normal functioning which has been damaged or absent, gene therapy may be able to introduce a normal copy of the gene into the cell in order to restore the function of the protein by using virus carrying the genetic materials.
However, some great result has occurred due to gene therapy like the treatment of beta-thalassemia. This is a kind of blood disorders which involves greatly reduced amounts of hemoglobin (the substance inside red blood cells that binds oxygen for it to be transported around our bodies). Researchers are busy to discover some faithful result but for now gene therapy is the only and trustworthy solution for eliminating the need for blood transfusions in patients who are suffering from beta-thalassemia.
Benefits of gene-editing
Gene therapy is a very successful procedure for the illness which generally caused by the damage of single gene but new gen-editing technique is able to splice and it may create some abnormalities in several genes. The latter’s potential use of this new gene-editing techniques may include some hereditary diseases such as Duchene muscular dystrophy (progressive weakness and loss of muscle function, which first begins in the lower limbs of young boys and worsens quickly), and cystic fibrosis (in which an afflicted young person may die in their early 30s due to lungs that are blocked by very thick mucus).
Anyway, this gene-editing technique may come in the new type of infertility treatment but as you read that it has so many side effects on other genes. So, I don’t say that people should not go for this procedure in order to get pregnant but as you always read in mu blog that I am the full supporter of natural treatment. Before opting any type of expensive and dangerous treatment for you illness, the first and most important tips is follow the natural treatment. Now a day’s several treatments are found which can be treated naturally because it has no side effects. In order to get the best result of natural treatment, follow the step by step guide, and get the satisfactory result as soon as possible. Infertility is also a kind of illness which can be treated naturally without any side effects and if is followed according to expert advice, women will be able to treat their all type of infertility. If you want more information about how to treat all type of infertility naturally and get pregnant in just 60 day, please visit the official website.